67) S. S. Kelkar, L. Xue, S. R. Richard, T. M. Reineke "Lanthanide-Containing Polycations for Monitoring Polyplex Dynamics via Lanthanide Resonance Energy Transfer",
Biomacromolecules 2013,
15, 1612–1624.
65) M. C. Dalsin, S. Tale, T. M. Reineke "Solution-State Polymer Assemblies Influence BCS Class II Drug Dissolution and Supersaturation Maintenance",
Biomacromolecules 2014,
15, 500–511.
64) X. Wang, S. S. Kelkar, A. G. Hudson, R. B. Moore, T. M. Reineke, L. A. Madsen "Quantitation of Complexed versus Free Polymers in Interpolyelectrolyte Polyplex Formulations",
ACS Macro Lett. 2013,
2, 1038–1041.
63) P. A. Burke, S. H. Pun, T. M. Reineke "Advancing Polymeric Delivery Systems Amidst a Nucleic Acid Therapy Renaissance",
ACS Macro Lett. 2013,
2, 928–934.
62) A. Sizovs, L. Xue, Z. Tolstyka, N. P. Ingle, Y. Wu, M. Cortez, T. M. Reineke "Poly(trehalose): Sugar-Coated Nanocomplexes Promote Stabilization and Effective Polyplex-Mediated siRNA Delivery",
J. Am. Chem. Soc. 2013,
135, 15417–15424.
61) L. Xue, N. P. Ingle, T. M. Reineke "Highlighting the Role of Polymer Length, Carbohydrate Size, and Nucleic Acid Type in Potency of Glycopolycation Agents for pDNA and siRNA Delivery",
Biomacromolecules 2013,
14, 3903–3915.
60) N. P. Ingle, L. Xue, T. M. Reineke "Spatio-Temporal Cellular Imaging of Polymer-pDNA Nanocomplexes Affords In Situ Morphology and Trafficking Trends",
Mol. Pharmaceutics 2013,
10, 4120–4135.
59) J. M. Ting, T. S. Navale, F. S. Bates, T. M. Reineke "Precise Compositional Control and Systematic Preparation of Multimonomeric Statistical Copolymers",
ACS Macro Lett. 2013,
2, 770-774.
58) H. Li, M. A. Cortez, H. R. Phillips, Y. Wu, T. M. Reineke "Poly(2-deoxy-2-methacrylamidoglycopyranose)-b-Poly(methacrylate amine)s: Optimization of Diblock Glycopolycations for Nucleic Acid Delivery",
ACS Macro Lett. 2013,
2, 230–235.
57) K. M. Fichter, N. P. Ingle, P. M. McLendon, T. M. Reineke "Polymeric Nucleic Acid Vehicles Exploit Active Interorganelle Trafficking Mechanisms",
ACS Nano 2013,
7, 347–364.
56) J. M. Bryson, J. W. Reineke, T. M. Reineke "Macromolecular Imaging Agents Containing Lanthanides: Can Conceptual Promise Lead to Clinical Potential?",
Macromolecules 2012,
45, 8939–8952.
55) C. Lee, Y. Liu, T. M. Reineke "Glucose-Based Poly(ester amines): Synthesis, Degradation, and Biological Delivery",
ACS Macro Lett. 2012,
1, 1388–1392.
54) K. Anderson, A. Sizovs, M. Cortez, C. Waldron, D. M. Haddleton, T. M. Reineke "Effects of Trehalose Polycation End-Group Functionalization on Plasmid DNA Uptake and Transfection",
Biomacromolecules 2012,
13, 2229-2239.
53) G. Grandinetti, T. M. Reineke "Exploring the Mechanism of Plasmid DNA Nuclear Internalization with Polymer-Based Vehicles",
Mol. Pharmaceutics 2012,
9, 2256-2267.
52) L. Yin, M. C. Dalsin, A. Sizovs, T. M. Reineke, M. A. Hillmyer "Glucose-Functionalized, Serum-Stable Polymeric Micelles from the Combination of Anionic and RAFT Polymerizations",
Macromolecules 2012,
45, 4322-4332.
51) D. J. Buckwalter, A. Sizovs, N. P. Ingle, T. M. Reineke "MAG versus PEG: Incorporating a Poly(MAG) Layer to Promote Colloidal Stability of Nucleic Acid/“Click Cluster” Complexes",
ACS Macro Lett. 2012,
1, 609-613.
50) G. Grandinetti, A. E. Smith, T. M. Reineke "Membrane and Nuclear Permeabilization by Polymeric pDNA Vehicles: Efficient Method for Gene Delivery or Mechanism of Cytoxicity?",
Mol. Pharmaceutics 2012,
9, 523-538.
49) M. Tranter, Y. Liu, S. He, J. Gulick, X. Ren, J. Robbins, W. K. Jones, T. M. Reineke "In Vivo Delivery of Nucleic Acids via Glycopolymer Vehicles Affords Therapeutic Infarct Size Reduction In Vivo",
Mol. Ther. 2012,
20, 601-608.
48) T. M. Reineke, M. E. Davis "Nucleic Acid Delivery via Polymer Vehicles",
Polymer Science: A Comprehensive Reference 2012,
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47) K. Kizjakina, J. M. Bryson, G. Grandinetti, T. M. Reineke "Cationic Glycopolymers for the Delivery of pDNA to Human Dermal Fibroblasts and Rat Mesenchymal Stem Cells",
Biomaterials 2012,
33, 1851-1862.
46) D. Bryson, W. Zhang, P. McLendon, T. M. Reineke, W. Santos "Toward Targeting RNA Structure: Branched Peptides as Cell-Permeable Ligands to TAR RNA",
ACS Chem. Biol. 2012,
7, 210-217.
45) N. Ingle, B. Malone, T. M. Reineke "Poly(glycoamidoamine)s: A Broad Class of Carbohydrate-Containing Polycations for Nucleic Acid Delivery",
Trends Biotechnol. 2011,
29, 443-453.
43) G. Grandinetti, N. P. Ingle, T. M. Reineke "Interaction of Poly(ethylenimine)–DNA Polyplexes with Mitochondria: Implications for a Mechanism of Cytotoxicity",
Mol. Pharmaceutics 2011,
8, 1709-1719.
42) A. E. Smith, A. Sizovs, G. Grandinetti, L. Xue, T. M. Reineke "Diblock Glycopolymers Promote Colloidal Stability of Polyplexes and Effective pDNA and siRNA Delivery under Physiological Salt and Serum Conditions",
Biomacromolecules 2011,
12, 3015–3022.
41) V. Taori, H. Lu, T. M. Reineke "Structure-Activity Examination of Poly(glycoamidoamine)s: Glycopolycations Containing Guanidine Units for Nucleic Acid Delivery",
Biomacromolecules 2011,
12, 2055-2063.
40) P. M. McLendon, D. J. Buckwalter, E. M. Davis, T. M. Reineke "Interaction of Poly(glycoamidoamine) DNA Delivery Vehicles with Cell-Surface Glycosaminoglycans Leads to Polyplex Internalization in a Manner Not Solely Dependent on Charge",
Mol. Pharmaceutics 2010,
7, 1757-1768.
39) P. M. McLendon, K. Fichter, T. M. Reineke "Poly(glycoamidoamine) Vehicles Promote pDNA Uptake Through Multiple Routes and Efficient Gene Expression via Caveolae-Mediated Endocytosis",
Mol. Pharmaceutics 2010,
7, 738-750.
38) A. Sizovs, P. M. McLendon, S. Srinivasachari, T. M. Reineke "Carbohydrate Polymers for Nonviral Nucleic Acid Delivery",
Top. Curr. Chem. 2010,
296, 131-190.
37) C. -C. Lee, G. Grandinetti, P. M. McLendon, T. M. Reineke "A Polycation Scaffold Presenting Tunable “Click” site: Conjugation to Carbohydrate Ligands and Examination of Hepatocyte-Targeted pDNA Delivery",
Macromol. Biosci. 2010,
10, 585-598.
36) Y. Liu and T. M. Reineke "Degradation of Poly(glycoamidoamine) DNA Delivery Vehicles: Polyamide Hydrolysis at Physiological Conditions Promotes DNA Release",
Biomacromolecules 2010,
11, 316-325.
34) J. M. Bryson, K. M. Fichter, W.-J. Chu, J.-H. Lee, J. Li, P. M. McLendon, L. A. Madsen, T. M. Reineke "Polymer Beacons for Luminescence and Magnetic Resonance Imaging of DNA Delivery",
Proc. Nat. Acad. Sci. USA 2009,
106, 16913-16918.
33) S. Srinivasachari, T. M. Reineke "Versatile Supramolecular pDNA Vehicles via “Click Polymerization” of β-cyclodextrin with Oligoethyleneamines",
Biomaterials 2009,
30, 928-938.
32) V. Taori, Y. Liu, T. M. Reineke "DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s",
Acta Biomater. 2009,
5, 925-933.
31) J. Bryson, W.–J. Chu, J.–H. Lee, T. M. Reineke "A β-Cyclodextrin “Click Cluster” Decorated with Seven Paramagnetic Chelates Containing Two Water Exchange Sites",
Bioconjugate Chem. 2008,
19, 1505-1509.
30) L. E. Prevette, K. Kizjakina, M. Lynch, T. M. Reineke "Correlation of Amine Number and pDNA Binding Mechanism for Trehalose-Based Polycations",
Langmuir 2008,
24, 8090-8101.
29) S. Srinivasachari, K. M. Fichter, T. M. Reineke "Polycationic β-Cyclodextrin “Click Clusters”: Monodisperse and Versatile Scaffolds for Nucleic Acid Delivery",
J. Am. Chem. Soc. 2008,
130, 4618–4627.
27) R. Lucas, M. Benjamin, T. M. Reineke "Comparison of a Tartaric Acid Derived Polymeric MRI Contrast Agent to a Small Molecule Model Chelate",
Bioconjugate Chem. 2008,
19, 24-27.
26) K. M. Fichter, L. Zhang, K. L. Kiick, T. M. Reineke "Peptide-Functionalized Poly(ethylene glycol) Star Polymers: DNA Delivery Vehicles with Multivalent Molecular Architecture",
Bioconjugate Chem. 2008,
19, 76-88.
25) C.–C. Lee, Y. Liu, T. M. Reineke "General Structure–Activity Relationship for Poly(glycoamidoamine)s: The Effect of Amine Density on Cytotoxicity and DNA Delivery Efficiency",
Bioconjugate Chem. 2008,
19, 428-440.
24) L. Prevette, T. Krodger, T. M. Reineke, M. L. Lynch "Deciphering the Role of Hydrogen Bonding In Enhancing DNA-Polycation Interactions",
Langmuir 2007,
23, 9773-9784.
23) S. Srinivasachari, Y. Liu, L. E. Prevette, T. M. Reineke "Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy",
Biomaterials 2007,
28, 2885-2898.
22) Y. Liu, T. M. Reineke "Poly(glycoamidoamine)s for Gene Delivery. Structural Effects on Cellular Internalization, Buffering Capacity, and Gene Expression",
Bioconjugate Chem. 2007,
18, 19-30.
21) Y. Liu, L. Wenning, M. Lynch, T. M. Reineke "Gene Delivery with Novel Poly(l-tartaramidoamine)s",
Polymeric Drug Delivery Volume I - Particulate Drug Carriers 2006,
Svenson, S. (Ed.), ACS Symposium Series, Vol. 923, American Chemical Society, Washington, DC, 217-227.
20) Y. Liu, T. M. Reineke "Poly(glycoamidoamine)s for Gene Delivery: Stability of Polyplexes and Efficacy with Cardiomyoblast Cells",
Bioconjugate Chem. 2006,
17, 101-108.
19) S. Srinivasachari, Y. Liu, G. Zhang, L. Prevette, T. M. Reineke "Trehalose Click Polymers Inhibit Nanoparticle Aggregation and Promote pDNA Delivery in Serum",
J. Am. Chem. Soc. 2006,
128, 8176-8184.
17) Y. Liu, T. M. Reineke "Hydroxyl Stereochemistry and Amine Number within Poly(glycoamidoamine)s Affect Intracellular DNA Delivery",
J. Am. Chem. Soc. 2005,
127, 3004-3015.
15) C. Gulgas, T. M. Reineke "Synthesis, Characterization, and Luminescence Properties of a New Series of Eu3+ – Containing Macrocycles",
Inorg. Chem. 2005,
44, 9829-9836.
14) M. E. Davis, S. H. Pun, N. C. Bellocq, T. M. Reineke, S. R. Popielarski, S. Mishra, J. D. Heidel "Self-Assembling Nucleic Acid Delivery Vehicles via Linear, Water-Soluble, Cyclodextrin-Containing Polymers",
Curr. Med. Chem. 2004,
11, 179-197.
13) Y. Liu, L. Wenning, M. Lynch, T. M. Reineke "New Poly(D-glucaramidoamine)s Induce DNA Nanoparticle Formation and Efficient Gene Delivery into Mammalian Cells",
J. Am. Chem. Soc. 2004,
126, 7422-7423.
12) T. M. Reineke, M. E. Davis "Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 2. Charge Center Type",
Bioconjugate Chem. 2003,
14, 255-261.
11) T. M. Reineke, M. E. Davis "Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 1. Carbohydrate Size and Its Distance from Charge Centers",
Bioconjugate Chem. 2003,
14, 247-254.
10) T. M. Reineke, M. E. Davis "The Effects of Charge Separation in Quaternary, Ammonium, DABCO-Containing Polymers on In Vitro Toxicity and Gene Delivery",
Mat. Res. Soc. Symp. Proc. 2002,
724, N10.2.1-N10.2.6.
9) J. Kim, B. Chen, T. M. Reineke, H. Li, M. Eddaoudi, D. B. Moler, M. O’Keeffe, O. M. Yaghi "Assembly of Metal-Organic Frameworks from Large Organic and Inorganic Secondary Building Units: New Examples and Simplifying Principles for Complex Structures",
J. Am. Chem. Soc. 2001,
123, 8239-8247.
8) M. Eddaoudi, D. B. Moler, H. Li, T. M. Reineke, B. L. Chen, M. O’Keeffe, O. M. Yaghi "Modular Chemistry: Secondary Building Units as a Basis for the Design of Highly Porous and Robust Metal-Organic Frameworks",
Acc. Chem. Res. 2001,
34, 319-330.
7) B. L. Chen, M. Eddaoudi, T. M. Reineke, J. W. Kampf, M. O’Keeffe, O. M. Yaghi "Cu2(ATC)·6H2O: Design of Open Metal Sites in Porous Metal−Organic Crystals (ATC: 1,3,5,7-Adamantane Tetracarboxylate)",
J. Am. Chem. Soc. 2000,
122, 11559-11560.
6) T. M. Reineke, M. Eddaoudi, D. Moler, M. O’Keeffe, O. M. Yaghi "Large Free Volume in Maximally Interpenetrating Networks: The Role of Secondary Building Units Exemplified by Tb2(ADB)3[(CH3)2SO]4•16[(CH3)2SO]",
J. Am. Chem. Soc. 2000,
122, 4843-4844.
5) M. O’Keeffe, M. Eddaoudi, H. Li, T. Reineke, O. M. Yaghi "Frameworks for Extended Solids: Geometrical Design Principals",
J. Solid State Chem. 2000,
152, 3-20.
3) T. M. Reineke, M. Eddaoudi, M. Fehr, D. Kelley, O. M. Yaghi "From Condensed Lanthanide Coordination Solids to Microporous Frameworks Having Accessible Metal Sites",
J. Am. Chem. Soc. 1999,
121,1651-1657.
2) M. Eddaoudi, H. Li, T. Reineke, M. Fehr, D. Kelley, T. L. Groy, O. M. Yaghi "Design and Synthesis of Metal-Carboxylate Frameworks with Permanent Microporosity",
Top. Catal. 1999,
9, 105-111.
1) C. L. Muller, J. R. Bever, M. A. Dordel, M. M. Kitabwalla, T. M. Reineke, J. B. Sausker, T. R. Seehafer, Y. Li, J. P. Jasinski "Regiochemistry of Intramolecular Photocycloaddition of 1,3-Dioxin-4-ones Tethered Through the Ketal Carbon",
Tetrahedron Lett. 1997,
38, 8663-8666.