Dr. Reineke is presenting exciting research going on in the group at the 18th Annual American Society of Gene and Cell Therapy Meeting in New Orleans from on Wednesday, May 13.
Gene and cell therapies must circumvent many biological barriers to become clinically effective. This talk will focus on the barriers that nanomaterial carriers encounter at the cellular level: from cell surface binding and internalization, to intracellular trafficking, and finally nuclear delivery. Examples of materials that promote specific cellular interactions and trafficking will be summarized and nanomaterial design features will be discussed.
Dr. Reineke’s talk it titled “Advancing the Development of Polymeric Nucleic Acid Delivery Vehicles: Methods to Understand and Control Synthesis, Assembly, and Properties.”